Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TNFA. AA range:141-190
Subcellular Location
Cell membrane
Single-pass type II membrane protein .
Single-pass type II membrane protein.
[C-domain 1]: Secreted.
[C-domain 2]: Secreted.
[Tumor necrosis factor, membrane form]: Membrane
[Tumor necrosis factor, soluble form]: Secreted .
Single-pass type II membrane protein .
Single-pass type II membrane protein.
[C-domain 1]: Secreted.
[C-domain 2]: Secreted.
[Tumor necrosis factor, membrane form]: Membrane
[Tumor necrosis factor, soluble form]: Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
7124
Observed Band
16kD
Other Name
Cachectin
TNF
TNF-a
TNF-alpha
TNFA
TNFSF2
Tumor necrosis factor
Tumor necrosis factor ligand superfamily member 2
TNF
TNF-a
TNF-alpha
TNFA
TNFSF2
Tumor necrosis factor
Tumor necrosis factor ligand superfamily member 2
Background
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B