Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TNF Receptor II. AA range:376-425
Subcellular Location
Single-pass type I membrane protein.
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted.
[Tumor necrosis factor-binding protein 2]: Secreted.
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted.
[Tumor necrosis factor-binding protein 2]: Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
7133
Observed Band
48kD
Other Name
CD antigen CD120b
Etanercept
TNF-R2
TNF-RII
TNFBR
TNFR-II
TNFR2
TNFRSF1B
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B
Tumor necrosis factor receptor type II
p75
p80 TNF-alpha receptor
Etanercept
TNF-R2
TNF-RII
TNFBR
TNFR-II
TNFR2
TNFRSF1B
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B
Tumor necrosis factor receptor type II
p75
p80 TNF-alpha receptor
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity.