Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TRIM24. AA range:1001-1050
Subcellular Location
Nucleus . Cytoplasm . Mitochondrion . Colocalizes with sites of active transcription. Detected both in nucleus and cytoplasm in some breast cancer samples. Predominantly nuclear. Translocated from nucleus to mitochondria to mediate antiviral immunity (Pub
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
8805
Observed Band
117kD
Other Name
E3 ubiquitin-protein ligase TRIM24
RING finger protein 82
RNF82
TIF1
TIF1-alpha
TIF1A
TRIM24
Transcription intermediary factor 1-alpha
Tripartite motif-containing protein 24
RING finger protein 82
RNF82
TIF1
TIF1-alpha
TIF1A
TRIM24
Transcription intermediary factor 1-alpha
Tripartite motif-containing protein 24
Background
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bo