Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MASTL. AA range:821-870
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus . Cleavage furrow . During interphase is mainly nuclear, upon nuclear envelope breakdown localizes at the cytoplasm and during mitosis at the centrosomes. Upon mitotic exit moves
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
84930
Observed Band
97kD
Other Name
GW
GW
GWL
GWL
MAST-L
MASTL
Microtubule-associated serine/threonine-protein kinase-like
Serine/threonine-protein kinase greatwall
THC2
hGWL
GW
GWL
GWL
MAST-L
MASTL
Microtubule-associated serine/threonine-protein kinase-like
Serine/threonine-protein kinase greatwall
THC2
hGWL
Background
This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for