Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor I. AA range:131-180
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Cell junction, tight junction . Cell surface . Membrane raft .
Single-pass type I membrane protein . Cell junction, tight junction . Cell surface . Membrane raft .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
7046
Observed Band
56kD
Other Name
ALK-5
ALK5
ALK5
Activin A receptor type II-like protein kinase of 53kD
Activin receptor-like kinase 5
SKR4
SKR4
Serine/threonine-protein kinase receptor R4
TGF-beta receptor type-1
TGF-beta type I receptor
TGFBR1
TGFR-1
Transfor
ALK5
ALK5
Activin A receptor type II-like protein kinase of 53kD
Activin receptor-like kinase 5
SKR4
SKR4
Serine/threonine-protein kinase receptor R4
TGF-beta receptor type-1
TGF-beta type I receptor
TGFBR1
TGFR-1
Transfor
Background
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutation