Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Transglutaminase 2. AA range:1-50
Subcellular Location
Cytoplasm, cytosol . Nucleus . Chromosome . Secreted, extracellular space, extracellular matrix . Cell membrane . Mitochondrion . Mainly localizes to the cytosol (PubMed:9575137). Present at much lower level in the nucleus and chromatin (PubMed:9575137).
[Isoform 2]: Cytoplasm, perinuclear region .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
7052
Observed Band
90kD
Other Name
Protein-glutamine gamma-glutamyltransferase 2
TG(C)
TGC
TGM2
TGase-2
TGase C
TGase H
Tissue transglutaminase
Transglutaminase-2
Transglutaminase C
Transglutaminase H
Background
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites