Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human SNX1.
Subcellular Location
Cytoplasmic side. Cell projection, lamellipodium . Enriched on tubular elements of the early endosome membrane. Binds preferentially to highly curved membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosph
Cytoplasmic side . Early endosome membrane
Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane
Endosome membrane
Peripheral membrane protein
Peripheral membrane protein
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
6642
Observed Band
60kD
Other Name
SNX1
Sorting nexin-1
Background
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface express