Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SKIL. AA range:616-665
Subcellular Location
acrosomal vesicle,nucleus,nucleoplasm,transcription factor complex,cytoplasm,PML body,transcriptional repressor complex,protein complex,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
6498
Observed Band
77kD
Other Name
SKIL
SNO
Ski-like protein
Ski-related oncogene
Ski-related protein
Background
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-respons