Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SENP7. AA range:991-1040
Subcellular Location
Cytoplasm .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
57337
Observed Band
112kD
Other Name
KIAA1707
SENP7
SSP2
SUMO-1-specific protease 2
SUSP2
Sentrin-specific protease 7
Sentrin/SUMO-specific protease SENP7
Background
MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1