Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ARHGEF1. AA range:162-211
Subcellular Location
Cytoplasm . Membrane . Translocated to the membrane by activated GNA13 or LPA stimulation.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
9138
Observed Band
105kD
Other Name
115 kDa guanine nucleotide exchange factor
ARHGEF1
Rho guanine nucleotide exchange factor 1
Sub1.5
p115-RhoGEF
p115RhoGEF
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multipl