Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human RRAGA/B. AA range:264-313
Subcellular Location
Cytoplasm . Nucleus . Lysosome . Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state (PubMed:8995684, PubMed:9394008). Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm espec
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
10670/10325
Observed Band
34kD
Other Name
Adenovirus E3 14.7 kDa-interacting protein 1
FIP-1
RRAGA
RRAGB
Rag A
RagA
Rag B
RagB
Ras-related GTP-binding protein A
Ras-related GTP-binding protein B
FIP-1
RRAGA
RRAGB
Rag A
RagA
Rag B
RagB
Ras-related GTP-binding protein A
Ras-related GTP-binding protein B
Background
function:Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby