Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human RAD18. AA range:301-350
Subcellular Location
Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Associates with chromatin (PubMed:25931565). Colocalizes with SLF1 in the nucleus and to centrosomes (PubMed:15632077). Relocalizes with SLF1 to nuclear foci in response to DNA
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Rat
Human Gen
56852
Observed Band
56kD
Other Name
E3 ubiquitin-protein ligase RAD18
Postreplication repair protein RAD18
RAD18
RING finger protein 73
RNF73
hHR18
hRAD18
Postreplication repair protein RAD18
RAD18
RING finger protein 73
RNF73
hHR18
hRAD18
Background
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Sim