Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human RAD17. AA range:621-670
Subcellular Location
Nucleus . Phosphorylated form redistributes to discrete nuclear foci upon DNA damage.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
5884
Observed Band
86kD
Other Name
Cell cycle checkpoint protein RAD17
R24L
RAD17
RF-C/activator 1 homolog
hRad17
Background
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity w