Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PYK2. AA range:546-595
Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Cell membrane
Cytoplasmic side. Cell junction, focal adhesion. Cell projection, lamellipodium. Cytoplasm, cell cortex. Nucleus. Interaction with NPHP1 induces the membrane-association of the kinase. Colocalizes with integrins at the cell periphery.
Peripheral membrane protein
Cytoplasmic side. Cell junction, focal adhesion. Cell projection, lamellipodium. Cytoplasm, cell cortex. Nucleus. Interaction with NPHP1 induces the membrane-association of the kinase. Colocalizes with integrins at the cell periphery.
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Rat
Monkey
Mouse
Rat
Human Gen
2185
Observed Band
115kD
Other Name
CADTK
CAK-beta
CAKB
Calcium-dependent tyrosine kinase
Calcium-regulated non-receptor proline-rich tyrosine kinase
Cell adhesion kinase beta
FADK 2
FAK2
Focal adhesion kinase 2
PTK2B
PYK2
Pro
Protein-tyrosine kinase 2-beta
RAFTK
CAK-beta
CAKB
Calcium-dependent tyrosine kinase
Calcium-regulated non-receptor proline-rich tyrosine kinase
Cell adhesion kinase beta
FADK 2
FAK2
Focal adhesion kinase 2
PTK2B
PYK2
Pro
Protein-tyrosine kinase 2-beta
RAFTK
Background
This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuro