Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB IF
WB IF
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PUMA. AA range:120-169
Subcellular Location
Mitochondrion . Localized to the mitochondria in order to induce cytochrome c release.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
27113
Observed Band
23kD
Other Name
BBC3
Bcl-2-binding component 3
JFY-1
PUMA
p53 up-regulated modulator of apoptosis
Bcl-2-binding component 3
JFY-1
PUMA
p53 up-regulated modulator of apoptosis
Background
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It