Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PPM1K. AA range:205-254
Subcellular Location
Mitochondrion matrix .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
152926
Observed Band
45kD
Other Name
PP2C-kappa
PP2C-like mitochondrial protein
PP2C-type mitochondrial phosphoprotein phosphatase
PP2CM
PP2C domain-containing protein phosphatase 1K
PPM1K
PTMP
Protein phosphatase 1K
Protein phosphatase 2C isoform kappa
mitochondrial
Background
This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permea