Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PMS2. AA range:461-510
Subcellular Location
Nucleus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5395
Observed Band
85kD
Other Name
DNA mismatch repair protein PMS2
Mismatch repair endonuclease PMS2
PMS1 protein homolog 2
PMS2
PMSL2
Mismatch repair endonuclease PMS2
PMS1 protein homolog 2
PMS2
PMSL2
Background
The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodime
also known as Lynch syndrome) and Turcot syndrome
also known as Lynch syndrome) and Turcot syndrome