Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PML. AA range:11-60
Subcellular Location
Cytoplasmic side . Early endosome membrane
Cytoplasmic side. Isoform PML-1 can shuttle between the nucleus and cytoplasm. Isoform PML-2, isoform PML-3, isoform PML-4, isoform PML-5 and isoform PML-6 are nuclear isoforms whereas isoform PML-7 and isoform PML-14 lacking the nuclear localization sign
Nucleus. Nucleus, nucleoplasm. Cytoplasm . Nucleus, PML body . Nucleus, nucleolus. Endoplasmic reticulum membrane
Peripheral membrane protein
Peripheral membrane protein
Cytoplasmic side. Isoform PML-1 can shuttle between the nucleus and cytoplasm. Isoform PML-2, isoform PML-3, isoform PML-4, isoform PML-5 and isoform PML-6 are nuclear isoforms whereas isoform PML-7 and isoform PML-14 lacking the nuclear localization sign
Nucleus. Nucleus, nucleoplasm. Cytoplasm . Nucleus, PML body . Nucleus, nucleolus. Endoplasmic reticulum membrane
Peripheral membrane protein
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5371
Observed Band
98kD
Other Name
MYL
PML
Promyelocytic leukemia protein
Protein PML
RING finger protein 71
RNF71
TRIM19
Tripartite motif-containing protein 19
PML
Promyelocytic leukemia protein
Protein PML
RING finger protein 71
RNF71
TRIM19
Tripartite motif-containing protein 19
Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies wh
all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],