Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PNN. AA range:211-260
Subcellular Location
Nucleus speckle. Cell junction, desmosome. Cell-cell contact area, predominantly desmosome of intercellular adherens junction. Not a nucleocytoplasmic shuttling protein.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
5411
Observed Band
85kD
Other Name
140 kDa nuclear and cell adhesion-related phosphoprotein
DRS
DRSP
DRS protein
Desmosome-associated protein
Domain-rich serine protein
MEMA
Melanoma metastasis clone A protein
Nuclear protein SDK3
PNN
Pinin
SR-like protein
DRS
DRSP
DRS protein
Desmosome-associated protein
Domain-rich serine protein
MEMA
Melanoma metastasis clone A protein
Nuclear protein SDK3
PNN
Pinin
SR-like protein
Background
function:Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene
the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Also participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Involved
the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Also participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Involved