Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PIAS1. AA range:10-59
Subcellular Location
Nucleus speckle . Nucleus, PML body . Interaction with CSRP2 may induce a partial redistribution along the cytoskeleton.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
8554
Observed Band
72kD
Other Name
DDXBP1
DEAD/H box-binding protein 1
E3 SUMO-protein ligase PIAS1
GBP
Gu-binding protein
PIAS1
Protein inhibitor of activated STAT protein 1
RNA helicase II-binding protein
Background
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a centra