Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PI 3-kinase p110alpha. AA range:470-519
Subcellular Location
intracellular,cytosol,plasma membrane,phosphatidylinositol 3-kinase complex,phosphatidylinositol 3-kinase complex, class IA,lamellipodium,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5290
Observed Band
110kD
Other Name
5-bisphosphate 3-kinase catalytic subunit alpha isoform
PI3-kinase subunit alpha
PI3K-alpha
PI3Kalpha
PIK3CA
Phosphatidylinositol 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit
PtdIns-3-kinase subunit alpha
Background
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has