Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human EHHADH. AA range:476-525
Subcellular Location
Peroxisome .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Human Gen
1962
Observed Band
80kD
Other Name
ECHD
EHHADH
PBE
PBFE
Peroxisomal bifunctional enzyme
Background
belongs to the 3-hydroxyacyl-CoA dehydrogenase family.,similarity:In the N-terminal section
belongs to the enoyl-CoA hydratase/isomerase family.,subunit:Monomer.,tissue specificity:Liver and kidney. Lower amounts seen in the brain.,
catalytic activity:(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.,catalytic activity:(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA.,catalytic activity:(S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.,disease:Absent in patients suffering
fatty acid beta-oxidation.,similarity:In the C-terminal section