Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Prostate Apoptosis Response protein-4. AA range:291-340
Subcellular Location
Cytoplasm. Nucleus. Mainly cytoplasmic in absence of apoptosis signal and in normal cells. Nuclear in most cancer cell lines. Nuclear entry seems to be essential but not sufficient for apoptosis (By similarity). Nuclear localization includes nucleoplasm a
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Cow
Human
Mouse
Rat
Human
Mouse
Rat
Human Gen
5074
Observed Band
36kD
Other Name
PAR4
PAWR
PRKC apoptosis WT1 regulator protein
Par-4
Prostate apoptosis response 4 protein
PAWR
PRKC apoptosis WT1 regulator protein
Par-4
Prostate apoptosis response 4 protein
Background
The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc