Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human YOD1. AA range:116-165
Subcellular Location
Cytoplasm . Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
55432
Observed Band
35kD
Other Name
DUBA-8
DUBA8
HIN-7
HIN7
HIV-1-induced protease 7
HsHIN7
OTUD2
OTU domain-containing protein 2
Ubiquitin thioesterase OTU1
YOD1
Background
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and remov