Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NYREN18. AA range:566-615
Subcellular Location
Nucleus . Predominantly nuclear.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Human Gen
51667
Observed Band
70kD
Other Name
NEDD8 ultimate buster 1
NUB1
NYREN18
Negative regulator of ubiquitin-like proteins 1
Renal carcinoma antigen NY-REN-18
Background
This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation