Nogo A rabbit pAb
  • Nogo A rabbit pAb
ELK

Nogo A rabbit pAb

Ref: ELK-ES2970-50ul
50ul

Información del producto

Nogo A rabbit pAb

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Información adicional
Storage Conditions -20°C/1 year
Applications ELISA
IF
IHC
WB
Concentration 1 mg/ml
Recomended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality Polyclonal
Immunogen The antiserum was produced against synthesized peptide derived from human Nogo A. AA range:450-499
Subcellular Location Cytoplasmic side . Anchored to the membrane of the endoplasmic reticulum (ER) through 2 putative transmembrane domains. Localizes throughout the ER tubular network (PubMed:27619977). Co-localizes with TMEM33 at the ER sheets. .
Extracellular side . Cell junction . Mainly located on endoplasmic reticulum tubules and sheet edges (PubMed:27786289). Upon ICAM1 engagement, redistributed toward endothelial junctions where interacts with CDH5 (PubMed:21183689). .
Multi-pass membrane protein
Multi-pass membrane protein
Multi-pass membrane protein .
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Cell membrane
[Isoform A]: Endoplasmic reticulum membrane
[Isoform B]: Endoplasmic reticulum membrane
[Isoform C]: Endoplasmic reticulum membrane
Iso type IgG
Tissue Source Rabbit
Reactivity Human
Mouse
Rat
Human Gen 57142
Observed Band 220kD
Other Name Foocen
KIAA0886
My043
NOGO
NSP
Neurite outgrowth inhibitor
Neuroendocrine-specific protein
Neuroendocrine-specific protein C homolog
Nogo protein
RTN-x
RTN4
Reticulon-4
Reticulon-5
SP1507
Background This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent ne