Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NFAT4. AA range:131-180
Subcellular Location
Cytoplasm . Nucleus . Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustaine
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
4775
Observed Band
115kD
Other Name
NF-AT4
NF-ATc3
NFAT4
NFATC3
NFATc3
NFATx
Nuclear factor of activated T-cells
T-cell transcription factor NFAT4
cytoplasmic 3
Background
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (