Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NEIL3. AA range:491-540
Subcellular Location
Nucleus . Chromosome . Recruited to replication stress sites via interaction with ubiquitinated CMG helicase. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
55247
Observed Band
35kD
Other Name
DNA glycosylase/AP lyase Neil3
DNA glycosylase FPG2
Endonuclease 8-like 3
Endonuclease VIII-like 3
NEIL3
Nei-like protein 3
DNA glycosylase FPG2
Endonuclease 8-like 3
Endonuclease VIII-like 3
NEIL3
Nei-like protein 3
Background
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the ass