Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NEIL1. AA range:291-340
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus . Chromosome . During mitosis, associates with centrosomes and condensed chromatin.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
79661
Observed Band
44kD
Other Name
DNA-(apurinic or apyrimidinic site) lyase Neil1
DNA glycosylase/AP lyase Neil1
Endonuclease 8-like 1
Endonuclease VIII-like 1
FPG1
NEH1
NEIL1
Nei-like protein 1
Nei homolog 1
Background
This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Mul