Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MSH3. AA range:51-100
Subcellular Location
nuclear chromosome,nucleoplasm,membrane,MutSbeta complex,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4437
Observed Band
127kD
Other Name
DNA mismatch repair protein Msh3
DUC1
DUG
DUP
Divergent upstream protein
MRP1
MSH3
Mismatch repair protein 1
hMSH3
Background
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer.