Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490
Subcellular Location
Nucleus . Chromosome . Recruited to chromatin in a MCM9-dependent manner. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
4292
Observed Band
85kD
Other Name
COCA2
DNA mismatch repair protein Mlh1
MLH1
MutL protein homolog 1
DNA mismatch repair protein Mlh1
MLH1
MutL protein homolog 1
Background
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phe