Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MGMT. AA range:1-50
Subcellular Location
Nucleus.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Rat
Human Gen
4255
Observed Band
22kD
Other Name
6-O-methylguanine-DNA methyltransferase
MGMT
MGMT
Methylated-DNA--protein-cysteine methyltransferase
O-6-methylguanine-DNA-alkyltransferase
MGMT
MGMT
Methylated-DNA--protein-cysteine methyltransferase
O-6-methylguanine-DNA-alkyltransferase
Background
Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein