Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MARK1/2/3/4. AA range:181-230
Subcellular Location
Cell membrane
Peripheral membrane protein . Cytoplasm, cytoskeleton . Cytoplasm . Cell projection, dendrite . Appears to localize to an intracellular network. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Rat
Human Gen
4139/2011/4140/57787
Observed Band
89kD
Other Name
ELKL motif kinase 1
EMK-1
EMK1
KIAA1477
MAP/microtubule affin
MAP/microtubule affinity-regulating kinase 1
MARK
MARK1
MARK2
PAR1 homolog c
Par-1c
Par1c
Serine/threonine-protein kinase MARK1
Serine/threonine-protein kinase MARK2
Background
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:May play a role