Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MADD. AA range:751-800
Subcellular Location
Cell membrane . Cytoplasm . Cell projection, axon .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
8567
Observed Band
183kD
Other Name
DENN
Differentially expressed in normal and neoplastic cells
IG20
Insulinoma glucagonoma clone 20
KIAA0358
MADD
MAP kinase-activating death domain protein
Rab3 GDP/GTP exchange factor
Differentially expressed in normal and neoplastic cells
IG20
Insulinoma glucagonoma clone 20
KIAA0358
MADD
MAP kinase-activating death domain protein
Rab3 GDP/GTP exchange factor
Background
Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this ge