Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TNFC. AA range:181-230
Subcellular Location
Membrane
Single-pass type II membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
4050
Observed Band
22kD
Other Name
LT-beta
LTB
Lymphotoxin-beta
TNF-C
TNFC
TNFSF3
Tumor necrosis factor C
Tumor necrosis factor ligand superfamily member 3
Background
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule al