Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human LATS1/2. AA range:1041-1090
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Midbody . Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body . Localizes to the centrosomes throughout interphase but migrates t
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
9113/26524
Observed Band
130-140kD
Other Name
KPM
Kinase phosphorylated during mitosis protein
LATS1
LATS2
Large tumor suppressor ho
Large tumor suppressor homolog 1
Serine/threonine-protein kinase LATS1
Serine/threonine-protein kinase LATS2
WARTS
WARTS protein kinase
h-warts
Background
The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late