Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NADAP. AA range:421-470
Subcellular Location
Nucleus . Cytoplasm . Mainly nuclear. Small amounts are found in the cytoplasm.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
22950
Observed Band
85kD
Other Name
HLC-3
HLC3
Human lung cancer oncogene 3 protein
Kanadaptin
Kidney anion exchanger adapter protein
SLC4A1AP
Solute carrier family 4 anion exchanger member 1 adapter protein
Background
caution:PubMed:15764369 initially suggested a role in targeting SLC4A1 (kidney anion exchanger 1) to the plasma membrane
it does not seem to do so as it does not interact with SLC4A1 and has no effect on SLC4A1 trafficking.,online information:Band 3 entry,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FHA domain.,subcellular location:Mainl