Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human JIP3. AA range:621-670
Subcellular Location
Cytoplasm . Golgi apparatus . Cytoplasmic vesicle . Cell projection, growth cone . Cell projection, axon . Cell projection, dendrite . Cytoplasm, perinuclear region . Localized in the soma and growth cones of differentiated neurites and the Golgi and vesi
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
23162
Observed Band
147kD
Other Name
C-Jun-amino-terminal kinase-interacting protein 3
JIP-3
JIP3
JNK-interacting protein 3
JNK MAP kinase scaffold protein 3
KIAA1066
MAPK8IP3
Mitogen-activated protein kinase 8-interacting protein 3
Background
The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and reg