Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human JIP1. AA range:69-118
Subcellular Location
Cytoplasm . Cytoplasm, perinuclear region . Nucleus . Endoplasmic reticulum membrane. Mitochondrion membrane. Accumulates in cell surface projections. Under certain stress conditions, translocates to the perinuclear region of neurons. In insulin-secreting
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
9479
Observed Band
113 78kD
Other Name
C-Jun-amino-terminal kinase-interacting protein 1
IB-1
IB1
Islet-brain 1
JIP-1
JIP1
JNK-interacting protein 1
JNK MAP kinase scaffold protein 1
MAPK8IP1
Mitogen-activated protein kinase 8-interacting protein 1
PRKM8IP
IB-1
IB1
Islet-brain 1
JIP-1
JIP1
JNK-interacting protein 1
JNK MAP kinase scaffold protein 1
MAPK8IP1
Mitogen-activated protein kinase 8-interacting protein 1
PRKM8IP
Background
This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcri