Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MEKKK 1. AA range:371-420
Subcellular Location
intracellular,cytoplasm,membrane,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
11184
Observed Band
91kD
Other Name
HPK1
Hematopoietic progenitor kinase
MAP4K1
MAPK/ERK kinase kinase kinase 1
MEKKK 1
MEK kinase kinase 1
Mitogen-activated protein kinase kinase kinase kinase 1
Background
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions an