Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human hnRNP Q. AA range:236-285
Subcellular Location
Cytoplasm . Microsome . Endoplasmic reticulum . Nucleus . The tyrosine phosphorylated form bound to RNA is found in microsomes (By similarity). Localized in cytoplasmic mRNP granules containing untranslated mRNAs (By similarity). .
[Isoform 1]: Nucleus, nucleoplasm . Expressed predominantly in the nucleoplasm. .
[Isoform 2]: Nucleus, nucleoplasm . Expressed predominantly in the nucleoplasm. .
[Isoform 3]: Nucleus, nucleoplasm . Expressed predominantly in the nucleoplasm. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
10492
Observed Band
62kD
Other Name
GRY-RBP
Glycine- and tyrosine-rich RNA-binding protein
HNRPQ
Heterogeneous nuclear ribonucleoprotein Q
NS1-associated protein 1
NSAP1
SYNCRIP
Synaptotagmin-binding
cytoplasmic RNA-interacting protein
hnRNP Q
Background
This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of