Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human GCSc-gamma. AA range:266-315
Subcellular Location
cytosol,integral component of membrane,glutamate-cysteine ligase complex,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2729
Observed Band
73kD
Other Name
GCLC
GCS heavy chain
GLCL
GLCLC
Gamma-ECS
Gamma-glutamylcysteine synthetase
Glutamate--cysteine ligase catalytic subunit
GCS heavy chain
GLCL
GLCLC
Gamma-ECS
Gamma-glutamylcysteine synthetase
Glutamate--cysteine ligase catalytic subunit
Background
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the ca