Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human GCN5L2. AA range:691-740
Subcellular Location
Nucleus . Chromosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Mainly localizes to the nucleus (PubMed:27796307). Also localizes to centrosomes in late G1 and around the G1/S transition, coinciding with the onset of centriole
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
2648
Observed Band
100kD
Other Name
GCN5
GCN5L2
General control of amino acid synthesis protein 5-like 2
HGCN5
Histone acetyltransferase GCN5
Histone acetyltransferase KAT2A
HsGCN5
KAT2A
Lysine acetyltransferase 2A
STAF97
GCN5L2
General control of amino acid synthesis protein 5-like 2
HGCN5
Histone acetyltransferase GCN5
Histone acetyltransferase KAT2A
HsGCN5
KAT2A
Lysine acetyltransferase 2A
STAF97
Background
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-