Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human GABRA6. AA range:61-110
Subcellular Location
Cell junction, synapse, postsynaptic cell membrane
Multi-pass membrane protein.
Multi-pass membrane protein. Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
2559
Observed Band
51kD
Other Name
GABA(A) receptor subunit alpha-6
GABRA6
Gamma-aminobutyric acid receptor subunit alpha-6
Background
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GA