Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from Fyb . at AA range: 620-700
Subcellular Location
Cytoplasm . Nucleus . Cell junction . Colocalizes with TMEM47 at cell-cell contacts in podocytes. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
2533
Observed Band
85kD
Other Name
ADAP
Adhesion and degranulation promoting adaptor protein
FYB
FYB-120/130
FYN-T-binding protein
FYN-binding protein
SLAP-130
SLAP130
SLP-76-associated phosphoprotein
p120/p130
Background
The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different is