Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Flt3 ligand. AA range:171-220
Subcellular Location
Single-pass type I membrane protein.
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted.
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2323
Observed Band
26kD
Other Name
FLT3LG
Flt3 ligand
Flt3L
Fms-related tyrosine kinase 3 ligand
SL cytokine
Flt3 ligand
Flt3L
Fms-related tyrosine kinase 3 ligand
SL cytokine
Background
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see
MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011],
MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011],