Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ZC3H8. AA range:81-130
Subcellular Location
Nucleus . Colocalizes with coilin in subnuclear cajal and histone locus bodies. Translocates in the LEC complex to cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
84524
Observed Band
40kD
Other Name
ZC3H8
ZC3HDC8
Zinc finger CCCH domain-containing protein 8
Background
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 C3H1-type zinc fingers.,