Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human FLI1. AA range:291-340
Subcellular Location
Nucleus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
2313
Observed Band
50kD
Other Name
FLI1
Friend leukemia integration 1 transcription factor
Proto-oncogene Fli-1
Transcription factor ERGB
Friend leukemia integration 1 transcription factor
Proto-oncogene Fli-1
Transcription factor ERGB
Background
11)(q21
22)(q24
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11
q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4
q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],
22)(q24
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11
q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4
q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],