Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human FIR. AA range:331-380
Subcellular Location
cytoplasm,cytosol,cytoskeleton,extrinsic component of membrane,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
9855
Observed Band
119kD
Other Name
FARP2
FERM
FERM domain including RhoGEF
FIR
KIAA0793
PH domain-containing family C member 3
PLEKHC3
Pleckstrin homology domain-containing family C member 3
RhoGEF and pleckstrin domain-containing protein 2
Background
function:Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 FERM domain.,similarit