Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human EXO1. AA range:61-110
Subcellular Location
Nucleus . Colocalizes with PCNA to discrete nuclear foci in S-phase.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
9156
Observed Band
94kD
Other Name
EXO1
EXOI
Exonuclease 1
Exonuclease I
HEX1
hExo1
hExoI
Background
This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative spl